Accueil / Membres / Anciens membres / MANEL Stéphanie

MANEL Stéphanie

Pr, Génétique du paysage

Formation - Cursus

2009-2014 : Membre IUF Junior

1999-2009 : MCF, LECA, Université Joseph Fourier, Grenoble

1995 - Thèse : Modélisation de la durée de développement préimaginal chez les poïkilothermes sous régime de températures variables, Université Claude Bernard, Lyon 1, Laboratoire de Biométrie et Biologie Evolutive.

Thème(s) de recherche

Mots clés : Biodiversité - Adaptation locale – Flux de gène -Génétique du paysage - Connectivité génétique

Principales questions scientifiques

Mécanismes à l’origine des patrons de distribution des espèces et de la diversité génétique
1) Quelle est l’influence de l’environnement sur ces distributions ?
2) Quels sont les mécanismes à l’origine de ces distributions (dérive génétique, flux de gènes, sélection) ?

Principales publications


Schoville I, Widmer I, Deschamps-Cottin M, Manel S (in press) Morphological clines and weak drift along an urbanization gradient in the butterfly, Pieris rapae. Plos One.

Lobreaux S, Manel S, MeloDelima C (in press) Development of an Arabis alpina genomic contig sequence dataset and application to SNP discovery. Molecular Ecology Resources.

Jones M, Forester B, Teufel A, Adams R , Anstett D, Goodrich B, Landguth E, Joost S, Manel S (2013) Integrating landscape genomics and spatially-explicit approaches to detect loci Under selection in clinal populations. Evolution

Manel S, Holderegger R (2013) Ten years of landscape genetics. Trends in Ecology and Evolution.

Andrello M, Moullot D, Beuvier J, Albout C, Thuiller W, Manel S (2013) Low connectivity between Mediterranean marine protected area : a biophysical modelling approach for the dusky grouper Epinephelus marginatus. Plos One, 8 : DOI : 10.1371/journal.pone.0068564.

Joost S, Vuilleumer S, Jensen JD, Schoville S, Leempoel K, Stucky S, Melo de Lima C, Rolland J, Manel S (2013) Uncovering the genetic basis of adaptive change : on the intersection of landscape genomics and theoretical populations genetics. Molecular Ecology, 22 : 3659-3665.

Lundgren P, Vera JC, Peplow L, Manel S., van Oppen MJH (2013) Genotype environment correlations in corals from the Great Barrier reef. BMC Genetics. 14 : DOI : 10.1186/1471-2156-14-9.

DeMita S., Thuillet AC, Gay L, Ahmadi N, Manel S, Ronfort J, Vigouroux Y (2013) Detecting selection along environmental gradients : analysis of eight methods and their effectiveness for outbreeding and selfing populations. Molecular Ecology. 22 : 1382-1399.

Buehler D, Poncet D, Holderegger R, Manel S, Taberlet P, Gugerli F (2013) An outlier locus relevant in habitat -mediated selection in an alpine plant across independent regional replicates. Evolutionary Ecology.27:285-300.

Bothwell H, S. Bisbing , N. Overgaard Therkildsen , L. Crawford, N. Alvarez, R. Holderegger, S. Manel (2013) Identifying genetic signatures of selection in a non-model species, alpine gentian (Gentiana nivalis L.), using a landscape genetic approach. Conservation Genetics.14:467-481.


Taberlet et al. (2012) Genetic diversity in widespread species is not congruent with species richness in alpine plant communities. Ecology Letters. 15:3729-3738.

Manel S, Gugerli F, Thuilller W, et al. (2012) Broad-scale adaptive genetic variation in alpine plants is driven by temperature and precipitation. Molecular Ecology.21:3729-3738.

Alvarez N, Manel S, Schmidt T et al. (2012) Contrasting diffusion of Quaternary gene pools across Europe : the case of the arctic-alpine Gentiana nivalis L. (Gentianaceae). Flora. 207:408-413.

Schoville S, Bonin A, François O, Lobreaux S, Melodelima C, Manel S (2012) Adaptive genetic variation on the landscape : methods and cases. Annual Review of Ecology, Evolution and Systematics. 43:23-43.

Jay F, Manel S, Durand E, Thuiller W, Taberlet P, Holderreger R, François O. (2012) Forecasting changes in population genetic structure of Alpine plants in response to global warming. Molecular Ecology. 21 : 2353-2368.

Decout S, Manel S, Miaud C, Luque S (2012) Integrative approach for landscape based graph connectivity analysis : a case study with the common frog (Rana temporaria), in human dominated landscapes. Landscape Ecology, 27 : 267-279.

Lizee, MH, Manel S., Mauffrey JF, Tatoni T, Deschamps-Cottin M (2012) Matrix configuration and patch isolation influences override the species-area relationship for urban butterfly communities. Landscape Ecology, 27 : 159-169.

Manel S, Albert C, Yoccoz NG (2012). Sampling in landscape genomics. In « Data Production and Analysis in Population Genomics » (Bonin A, Pompanon F eds). Methods in Molecular Biology Series, Humana Press. pp. 93-112.


Lentendu G, Zinger L, Manel S, Coissac E, Choler P, Gérémia R, Melo Delima C. (2011) Assessment of soil fungal diversity in different alpine tundra habitats by means of pyrosequencing. Fungal Diversity, 49:113-123.

Safner T, Miller MP , Mcrae B, Fortin MJ, Manel S (2011) Comparison of Bayesian clustering and edge detection methods for inferring boundaries in landscape genetics. International Journal of Molecular Sciences, 12:865-889. .


Safner T, Miaud C, Gaggiotti O, Decout S., Rioux D, Zundel S, Manel S (2011) Combining demography and genetic analysis to assess the population structure of an amphibian in a human-dominated mandscape. Conservation Genetics, 12:161-173.

Holderegger R, Buehler D, Gugerli F, Manel S (2010) Landscape genetics of plants. Trends in Plant Science, 15:675-682.

Epperson BK, McRae B, Scribner K, Cushman SA, Rosenberg MS, Fortin, MJ, James PMA, Murphy M, Manel S, Legendre P, Dale MRT (2010) Utility of computer simulations in landscape genetics. Molecular Ecology, 19 : 3549-3564.

Manel S, Joost S, Epperson BK, Holderegger R, Storfer A, Rosenberg MS, Scribner K, Bonin A, Fortin MJ (2010) Perpective on the use of landscape genetics to detect genetic adaptive variation in the field. Molecular Ecology, 19 : 3760-3772.

Manel S, Poncet BN, Legendre P, Gugerli F, Holderegger R (2010) Common factors drive adaptive genetic variation at different scale in Arabis alpina. Molecular Ecology, 19:2896-2907.

Poncet BN, Herrmann D,Gugerli F, Taberlet P, Holderegger R, Gielly L, Rioux D, Thuiller W, Aubert A, Manel S (2010) Tracking gene of ecological relevance in two independant regional population samples of Arabis alpina. Molecular Ecology, 19 : 2896-2907.

Herrmann D, Poncet BN, Manel S, Rioux D, Gielly L, Taberlet P, Gugerli F (2010) Selection criteria for scoring amplified length polymorphisms (AFLP) positively affect the reliability of population genetic parameter estimates. Genome, 53:302-310.

Segelbacher G, Cushman SA, Epperson BK, Fortin MJ , Francois O, Hard O, Holderegger R, Taberlet P, Waits LP, Manel S (2010) Landscape Genetics : Concepts and Challenges in a conservation context. Conservation Genetics, 11:375-385.


Manel S, Conord C and Despres L (2009) Genome scan to assess the respective role of host-plant and environmental constraints on the adaptation of a widespread insect. BMC Evolutionary Biology, 9:288.
Alvarez, N. Thiel-Egenter C, Tribsch A., Holderegger R., Manel S. et al. (2009). History or ecology ? Substrate type as a major driver of spatial genetic structure in Alpine plants. Ecology Letters, 12:632-240.

Manel S. and Segelbacher G. (2009). Meeting review : perspectives and challenges in landscape genetics. Molecular Ecology, 18 : 1821-1822.

Poncet B., Garrat P., Manel S., Bur N., Sachet JM, Roques A., Deprés L. (2009). The effect of climate on masting in the European larch and on its specific seed predators. Oecologia, 159 : 527-537 2.


Holderegger R., Herrmann D., Poncet B., Gugerli F., Taberlet P., Gielly L., Rioux D., Thuiller W., Brodbeck S., Aubert S., Manel S. (2008) Land ahead : Using genome scans to identify molecular markers of adaptive relevance. Plant Ecology and Diversity : 1 : 273-283.

Segelbacher G. , Manel S. and Tomiuk J. (2008) Temporal and spatial analyses disclose consequences of habitat fragmentation on the genetic diversity in capercaillie (Tetrao urogallus) Molecular Ecology, 17 : 2356-2367


A. Bonin, D. Ehrich and S. Manel. (2007) Statistical analysis of amplified fragment length polymorphism data : a toolbox for molecular ecologists and evolutionists Molecular Ecology, 16 : 3737–3758.

S. Manel, F. Berthoud, E. Bellemain, M. Gaudeul, G. Luikart, J. E. Swenson, L. P. Waits, P. Taberlet, and Intrabiodiv Consortium. (2007) A new individual-based spatial approach for identifying genetic discontinuities in natural populations. Molecular Ecology, 10 : 2031-2043.

Cercueil A. , François O. and Manel S. (2007) The genetical bandwidth mapping : a spatial and graphical representation of population genetic structure based on the wombling method. Theoretical Population Biology, 71 : 3 332-341.

Crida A. and Manel S. (2007) WOMBSOFT : a R package that implements the wombling method to identify genetic boundary. Molecular Ecology Note, 7 : 588-591.


Bellemain E, Zedrosser A, Manel S, Taberlet P & Swenson J. (2006) To choose or not to choose : the dilemma of female mate selection in species with sexually selected infanticide. The Proceedings of the Royal Society of London, series B, 273 : 283-291.


Manel S., Gaggiotti O. & Waples R. (2005) Assignment methods : Which approaches best address which biological questions ? Trends in Ecology and Evolution, 20 : 136-142.


Gaudeul M., Till I., Barjon F. & Manel S. (2004) Genetic diversity and differentiation in Eryngium alpinum (L. Apiacae) : comparison of AFLP and microsatellite markers. Heredity, 92 : 508-518.

Manel S., Bellemain E., Swenson S. & François O. (2004) Assumed and inferred spatial structure of populations : the Scandinavian brown bears revisited. Molecular Ecology, 13 : 1327-1331.

Blum M., Damerval C., Manel S. & François O. (2004) Brownian models and coalescent structures. Theoretical Population Biology, 65 : 249-261.

Manel S., Schwartz M., Luikart G. & Taberlet P. (2003) Landscape genetics : combining landscape ecology and population genetics. Trends in Ecology and Evolution, 20 : 136-142.

D’Amico F., Darblade S. ; Avignon S. ; Manel S & Ormerod S. J. (2004) Odonates as indicators of Shallow lake restoration by liming. Comparing adult and larval responses. Restoration Ecology. 8 : 439-446.

Before 2004

Cercueil A., Bellemain E. & Manel S. (2002) PARENTE : computer program for parentage analysis. The Journal of Heredity, 93 : 458-459.

Manel S., Berthier P. & Luikart G. (2002) Detecting Wildlife Poaching : Identifying the Origin of Individuals Using Bayesian Assignment tests and Multi-locus Genotypes. Conservation Biology, 16 : 650-659.

Manel S., Brewin P.A., Williams C. & Ormerod S. (2001) Evaluating presence-absence models in Ecology. Journal of Applied Ecology, 38 : 921-931.

Manel S., Buckton S.T. & Ormerod S.J. (2000) Problems and possibilities in large scale ecological surveys : the effect of land use on Himalayan river birds. Journal of Applied Ecology, 37 :756-770.

Manel S., Dias J-M., Buckton S.T. & Ormerod S.J. (1999) Alternative methods for predicting species distribution : an illustration with Himalayan river birds. Journal of Applied Ecology, 36 : 734-747.

Manel S., Dias, J-M. & Ormerod S.J. (1999) Comparing discriminant analysis, neural networks and logistic regression for predicting species distributions : a case study with a Himalayan river bird. Ecological Modelling, 120 : 337-347.

Manel S. & Debouzie D. (1997) Modeling insect development time of two or more larval stages in the field under variable temperatures. Environmental Entomology, 26 :163-169.

Manel S. & Debouzie D. (1997) Logistic regression and continuation ratio models to estimate insect development under variable temperatures. Ecological Modelling, 98 : 237-243

Manel S. & Debouzie D. (1995) Prediction of egg and larval development time in the field under variable temperatures. Acta Oecologica, 16 :205-218.

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